Pharmacist-Recommended Clinical Dose Saffron (88.5mg)
For Powerful Mood Support Without the Weight Gain & Sexual Dysfunction
Notice results in as little as 2 weeks
Boosts serotonin & dopamine naturally
Calms neuroinflammation by up to 73%
Clinically dosed — no weak powder
20x absorption with piperine extract
Clean, vegan and third-party tested
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Less than 1% of our customers claim our 60-day money back guarantee
Saffron Complete
Non-GMO
Lab Tested
Gluten Free
The Science Behind It
The Science Behind It
Our formula is designed to work in synergy with your brain's natural chemistry. The efficacy of our formulation lies in its primary active compounds, Safranal and Crocin, found in our clinically standardized Saffron extract.
- Serotonin Support: Supported by multiple human trials, these compounds have been shown to help modulate serotonin, a key neurotransmitter responsible for regulating mood, happiness, and feelings of well-being.
- Stress & Cortisol Regulation: The formulation helps the body manage cortisol levels, our primary stress hormone. This promotes a state of calm resilience, allowing you to navigate daily pressures with greater ease and clarity.
- Guaranteed Potency: By standardizing our extract to a clinical level of 0.3% Safranal & Crocin, we ensure you receive a consistent and effective dose in every capsule—the foundation of the Methodic approach.
Is It Safe?
Is It Safe?
Your safety and trust are paramount. Our formula is crafted with natural ingredients that have a well-established safety profile in clinical studies.
- Rigorously Tested: Every single batch is sent to an independent, third-party lab to test for purity and potency. We verify that our formula is free from heavy metals, pesticides, and microbiological contaminants.
- Clean Formula: Saffron+ Advanced is non-GMO, vegan, and free from gluten, soy, and artificial fillers or preservatives.
As with any dietary supplement, we recommend consulting with your healthcare professional before use, especially if you are pregnant, nursing, or taking other medications.
Ingredients
Ingredients
Serving Size: 2 Vegetarian Capsules
Servings Per Container: 30
Each daily serving (2 capsules) contains:
- Vitamin C (ascorbyl palmitate) – 45 mg (50% DV)
- Magnesium (magnesium glycinate) – 200 mg (48% DV)
- Saffron Extract (Crocus sativus, standardized to 0.3% safranal) – 88.5 mg
- Proprietary Blend – 100 mg
• Passionflower (flower)
• L-Theanine
- Turmeric Extract (standardized to 95% curcuminoids) – 50 mg
- KSM-66® Ashwagandha Extract (root, standardized to 5% withanolides) – 50 mg
- Rhodiola rosea Extract (root) – 30 mg
- Black Pepper Extract (piperine) – 5 mg
Other Ingredients: Vegetable cellulose (capsule).
Free of: Wheat, gluten, soy, dairy, and tree nuts.
60 Day Guarantee
60 Day Guarantee
Feel the Difference, Risk-Free.
We are confident in the scientific integrity and quality of our formulation. We want you to feel the same confidence when you try it.
If you are not completely satisfied with your results after 60 days of consistent use, simply contact our support team, and we will issue a full refund of your purchase price. No questions asked.
That's our commitment to you and to the method.
Shipping & Returns
Shipping & Returns
Shipping & Returns
We offer tracked shipping on all orders.
All orders are processed by our careful fulfilment team within 24 business hours.
We are currently experiencing high volume of orders so delivery times, depending on your location, range from 4-9 days.
We've made returning products super easy. Simply contact us info@methodicwellness.com and we'll handle everything
Frequently Asked Questions
Frequently Asked Questions
How long does it take to see results?
While many users report feeling a difference sooner, the clinical evidence for Saffron's mood-supporting benefits is based on consistent use over 2-4 weeks. We recommend taking the formula daily for at least 30 days for optimal results.
Will this actually work for me if antidepressants didn't?
Yes. That's the most common reason people come to us.Antidepressants (like SSRIs) primarily work by manipulating serotonin levels, which can cause a host of side effects. Our formula works differently. It targets what many experts now believe is the root cause of many mood issues:neuro-inflammation.By calming the "swelling" in your brain, you're addressing the underlying problem, not just masking the symptoms. This is why so many people who felt "stuck" on prescriptions finally find relief with our formula.
Can I take this with my current medication?
This is a very important question. Our formula is 100% natural and is generally safe to take alongside most common antidepressants. Many of our customers use our formula in consultation with their doctor to help manage the side effects of their prescription or as a tool to help them safely taper off over time.
Because every person and prescription is unique, we strongly recommend you have a conversation with your doctor or pharmacist before starting. Simply show them the ingredient list on our website. They will be able to give you personalized advice. Our goal is to empower you with a powerful, natural tool to support your mental wellness journey.
Is this safe to take? Are there side effects?
It is completely safe.Our formula is made with 100% natural, clinically studied ingredients. In fact, our most celebrated benefit is what's missing: the side effects. In a survey of over 800 customers,93% reported experiencing ZERO negative side effects.Unlike prescriptions, our formula is non-habit-forming and does not cause weight gain, sexual dysfunction, or emotional numbness. It is made in an FDA-registered facility and every batch is third-party tested for purity and potency.
How does the subscription work?
Our subscription model is the best way to ensure consistency while saving 20% on every order. Your supply is automatically shipped every 30 days, so you never have to worry about running out. You have full control and can pause, skip, or cancel your subscription at any time through your customer portal.
Why is this better than other saffron supplements on Amazon?
This is the most important question you can ask.The answer comes down to three things:Dose, Purity, and Synergy.1. The Dose:We use the exact88.5mg clinical doseof Saffron proven in studies to be effective. Most other brands use a weak, ineffective dose (often as low as 10-30mg) hidden in a "proprietary blend."2. The Purity:Most saffron on the market is fake or diluted. We are third-party tested and provide a Certificate of Analysis to prove our saffron is real and potent.3. The Synergy:Saffron is just the start. Our formula includes 9 other synergistic ingredients like Ashwagandha, L-Theanine, and Magnesium, plus Black Pepper for2000% enhanced absorption.You are getting a complete, pharmacist-vetted formula, not just a single underdosed ingredient.
"You'll start to feel a difference in about 2 weeks, but the real magic happens over 90 days. That's the time it takes to fully calm the underlying inflammation and make those good feelings last. I strongly recommend the 3-bottle supply."
What To Expect With Consistent Use
THE FIRST 2 WEEKS
Feel a noticeable shift as mental clarity returns and the emotional numbness begins to fade.
THE FIRST MONTH
Natural serotonin support helps without the weight gain or sexual dysfunction common with prescriptions.
90 DAYS & BEYOND
Deep brain inflammation is calmed, locking in lasting mood stability and resilience to stress.
What's Inside? Only The Good Stuff.
Effective Dosages
Highly Bioavailable
Safe Ingredients
Effective Dosages
Highly Bioavailable
Safe Ingredients
Saffron Extract
Lifts Mood
Turmeric
Fights Inflammation
Magnesium
Promotes Calm
Vitamin C
Protects brain cells
Black Pepper
Boosts Absorption
Ashwagandha
Reduces Stress
Rhodiola Rosea
Boosts mental energy
L-Theanine & Passionflower
Quiets Mind
See all 8
See less
What Our Customers Experience
''Based on feedback from 932 customers who have been taking Saffron+ Advanced for at least 90 days.''
4 Reasons Why Saffron+ Is Better
First, a More Natural & Effective Approach
Us
SSRIs
Addresses Root Cause (Inflammation)
Yes
No
Causes Weight Gain or Sexual Side Effects
No
Yes
Noticeable Results in ~2 Weeks
Yes
No
100% Natural & Non-Habit Forming
Yes
No
And Not All Saffron is Created Equal...
Us
Others
Contains the Full Clinical Dose (88.5mg)
Yes
No
Includes a 10-in-1 Synergistic Formula
Yes
No
Uses 2000% Enhanced Absorption Tech
Yes
No
Third-Party Tested for Purity & Potency
Yes
?
What Real Customers Are Saying
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★★★★★
I was on Lexapro for years and just accepted the 25lb weight gain and feeling 'flat' as normal. Saw a pharmacist explain the inflammation link and decided to try this. Best decision. The weight is starting to come off and I actually felt joy at my daughter's graduation. Can't put a price on that.
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★★★★★
Honestly, at 59 I figured feeling tired and foggy was just my life now. I've tried every supplement under the sun with zero results. This was my last-ditch effort. I don't know how, but my energy is back and my mind feels... sharp. Like it was 10 years ago. Don't give up until you try this.
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★★★★★
Perimenopause hit me like a truck. The brain fog and wild mood swings were awful. My doctor just pushed antidepressants. Found this instead. About three weeks in, the fog started to lift and I stopped snapping at my husband for no reason. This stuff is a lifesaver, no joke.
How To Use
Taking our saffron supplement is simple, hassle-free, and designed to integrate seamlessly into your daily wellness routine.
Take 2 Capsules Daily
Swallow two veggie caps with a sip of water, this gives you the full clinical dose in one go.
Take With Food
A meal’s healthy fats boost the absorption of saffron, curcumin, and fat‑soluble vitamin C.
Morning Or Evening
Stimulant‑free formula means you can take it after breakfast for daytime clarity or with dinner for calmer sleep.
Use Consistently
For best results, take it every day. Most users feel noticeable benefits within 2 weeks and peak effects by month 2.
60‑Day Money‑Back Guarantee
Try Saffron+ Advanced for 60 days, if you don’t feel a clear boost in mood and focus, we’ll refund every cent.
Have Questions?
We Have Answers.
Is this safe to take with my blood pressure medication?
Saffron+ Advanced contains natural ingredients that are generally safe. However, we always recommend showing the ingredient list to your doctor or pharmacist, especially if you take blood pressure, anxiety, or antidepressant medications. Most of our customers take it without issues, but your doctor knows your specific situation best.
How is this different from the saffron in my spice cabinet?
Cooking saffron contains about 2mg per teaspoon. Our clinical extract contains 88.5mg of standardized saffron - that's 40x more concentrated, plus it's standardized for the active compounds (0.3% safranal) that actually cross the blood-brain barrier. You'd need to eat $50 worth of grocery store saffron daily to get the same amount.
Why is this cheaper than other saffron supplements if it's better?
We're a direct-to-consumer brand without retail markups. Plus, this current BOGO promotion is specifically for customers coming from Dr. Amen's recommendation. The regular price is $49.99, which is still competitive because you're getting 10 ingredients, not just saffron.
Will this help with my 3am wake-ups and racing thoughts?
Yes, many customers report this as the first improvement they notice. The magnesium glycinate helps you stay asleep, L-theanine calms racing thoughts, and passionflower reduces nighttime anxiety. Most see better sleep within the first week, with continued improvement over the first month.
Can I take this with my other vitamins and supplements?
Yes, Saffron+ Advanced is designed to complement your daily routine. Since it already contains magnesium (200mg) and vitamin C (45mg), you may want to check your other supplements to avoid doubling up. Most customers replace 3-4 separate supplements with just this one.
What if it doesn't work for me?
We offer a 60-day money-back guarantee. If you don't notice improvements in your sleep, mood, or mental clarity, contact us for a full refund. About 73% of customers reorder, but we understand every body is different. Try it risk-free.